August 11, 2021

TOXOUT KITS

By Ivan

Endotoxin is the lipopolysaccharide (LPS) complex located in the outer membrane of gram-negative bacteria. A single E.coli bacterium contains ~ 2 million LPS molecules (2 – 20 FG / cell). During experimental procedures, large amounts of endotoxins are shed and can easily contaminate labware, buffers, and downstream products. In vitro, endotoxin causes a variety of problems in cell-based research. In vivo, endotoxin may cause various side effects, including inflammatory response, organ failure, or septic shock in host organisms.

Therefore, it is critical to remove endotoxin from samples and products. BioVision’s ToxOut  Rapid Endotoxin Removal Kit can quickly and effectively eliminate endotoxins to <0.05 EU / ml in solutions containing proteins or pharmacologically important components via the immobilized polymyxin B, which is known for capturing endotoxin and preventing toxic effects.

Endotoxin is the lipopolysaccharide complex (LPS) located on the outer membrane of gram-negative bacteria. A single E. coli bacterium contains ~ 2 million LPS molecules (2 – 20 FG / cell). During experimental procedures, large amounts of endotoxins are removed that can easily contaminate labware, buffers, and downstream products. In vitro, endotoxin causes a variety of problems in cell-based research.

In vivo, endotoxin can cause a number of side effects, including inflammatory response, organ failure, or septic shock in host organisms. Therefore, it is essential to remove endotoxins from samples and products. BioVision’s ToxOut ™ Rapid Endotoxin Removal Kit can quickly and efficiently remove endotoxins down to <0.05 EU / ml in solutions containing pharmacologically important proteins or components via immobilized Polymyxin B, known to capture endotoxins and prevent toxic effects.